Sunday, January 23, 2022

What is Erythrocyte sedimentation rate ESR

What is Erythrocyte sedimentation rate ESR? 

This is a measurement of rate with which our blood cells settle down or sediment in one hour. In this test rate at which blood cells settle in a test tube of standard specification is studied , this is a hematological test and it is not specific for diagnosis of disease rather it helps in finding one or the possible causes which affect health and to asses sickness index of an individual. There are many sophisticated diagnostic test available , even though it is used along with those tests.

While doing this test blood is added with anticoagulant like heparin and EDTA and placed in to test tubes. Final result is reported in Erythrocytes settling to depth in mm per hour mm/hour.

In case of inflammation proteins like fibrinogen are produced in higher amount which forms staking or rouleaux and sedimentation of erythrocytes also in case increases .

This test is not considered as final and diagnostic test for any disease rather serve as a guidance test for physician for proceeding for further tests for diagnosis.

In case of rheumatoid arthritis and pregnant women ESR is increased while it is depressed in case of disorders of hematopoietic tissue like sickle cell anemia, hereditary spherocytosis, polycythemia and congestive cardiac failure.

Normal values of ESR

Men ( Age 20 = ESR 12)

Men ( Age 55 = ESR 14)

Men ( Age 90 = ESR 19)

Women (Age 20 =ESR 18)

Women (Age 55 =ESR 21)

Women (Age 90 =ESR 23)

There may be deviation of 5% which can be clinically related

In case of newborn ESR is zero to 3 mm/ hour

One month to 16 years of age it is found 4 to 12 mm / hour

In case of following disease conditions ESR is found higher .

Chronic kidney diseases , Chronic Auto-immune diseases, chronic arthritis, temporal, systemic lupus erythematosus , multiple myeloma, polymyalgia rheumatica


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