Capsicum is not a pain killer, but the oleo resin in capsicum which is also called capsaicin is when used in topical preparations in very little concentration along with other topical drugs like diclofenac it provides relief from pain faster. The mechanism of action by which it acts as a painkiller is its counterirritant action. Capsaicin is a very potent irritant, when it is in direct contact with tissue, it gives a burning sensation and sometimes can cause conditions like superficial burns over skin tissue.
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